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Next-Gen Sequencing tools from the Horvath Lab

SNPlice Output Files

Output Files

Tabular formats including txt, tsv, csv, xlsx, xls.

Text files (txt) are tab-separated fields without headers. Other tabular formats provide headers. Fields are output in deterministic column order as shown on SNPlice Output Fields page.

Output Fields

Note that fields and their values passed through from the input SNP file (VCF or tabular formats) are not documented here, refer to the source of the input SNP file for this.

CHROM

Chromosome identifier of SNP

POS

Chromosome position of SNP

REF

Reference allele nucleotide

ALT

Variant allele nucleotide

NumofJuncs

Number of exon-intron junctions within the specified distance (-d/–distance/Distance)

Distance

Nucleotide distance from SNP locus to exon-intron junction.

Junctions

Chromosome position of the exon-intron-exon junctions represented by each intron’s boundaries.

SNPJuncIntronCount

Number of spliced spanning reads with ALT nucleotide.

SNPJuncNoIntronCount

Number of unspliced spanning reads with ALT nucleotide.

NoSNPJuncIntronCount

Number of spliced spanning reads with REF nucleotide.

NoSNPJuncNoIntronCount

Number of unspliced spanning reads with REF nucleotide.

Probability

Probability score of observed read counts.

LOD

Log-odds of unspliced spanning reads vs spliced spanning reads with ALT nucleotide with respect to unspliced spanning reads vs spliced spanning reads.

P-Value

Fisher exact test of 2x2 contingency table for spliced vs unspliced spanning reads containing ALT vs REF nucleotides.

Bonferroni

Bonferroni multiple test correction of Fisher exact test p-value.

FDR

Benjaminni-Hochberg false-discovery-rate multiple test correction of Fisher exact test p-value.

SNPMateCount (M,F)

Number of spanning reads with the ALT nucleotide whose mate contains the exon-intron junction.

NoSNPMateCount (M,F)

Number of spanning reads with the REF nucleotide whose mate contains the exon-intron junction.

SNPCount (F)

Number of spanning reads with ALT nucleotide.

NoSNPCount (F)

Number of spanning reads with REF nucleotide.

MatesCount (M,F)

Number of spanning reads containing the SNP site whose mate contains the exon-intron junction.

NotMatesCount (M,F)

Number of spanning reads containing the SNP site and the exon-intron junction.

IntronCount (F)

Number of spliced spanning reads.

NoIntronCount (F)

Number of unspliced spanning reads.

SpanningReads (F)

Number of reads (or reads + mates) containing the SNP site and exon-intron junction.

RemovedDuplicateReads (F)

Number of duplicate reads removed.

SNPLociReads (F)

Number of reads containing SNP site.

Key:

(M) Fields output if -M/--matepairs/Mates option is true. 
(F) Fields output if -F/--full/All Fields option is true. 

See Also

SNPlice Home, SNPlice, SNPlice-Combine, Input Files